IMMUNOLOGIC SEQUELAE OF THERMAL INJURY

IMMUNOLOGIC SEQUELAE OF THERMAL INJURY

Summary 1) Thermal injury induces a marked inhibition in the ability of tuberculin‐sensitive guinea pigs to respond to intradermal challenge with tuberculin. The effect is most marked during the first and second weeks after burning, but may persist as long as five weeks. 2) Thoracic duct lymph sampl...

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Veröffentlicht in:Annals of the New York Academy of Sciences 1968-08, Vol.150 (3), p.1004-1008
Hauptverfasser: Rapaport, F. T., Milgrom, F., Kano, K., Gesner, B., Solowey, A. C., Casson, P., Silverman, H. I., Converse, J. M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies
Burns - immunology
Guinea Pigs
Hemagglutination
Hypersensitivity, Delayed
Immune Tolerance
Lymph - immunology
Male
Methods
Rats
Skin Tests
Tuberculin
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Zusammenfassung:Summary 1) Thermal injury induces a marked inhibition in the ability of tuberculin‐sensitive guinea pigs to respond to intradermal challenge with tuberculin. The effect is most marked during the first and second weeks after burning, but may persist as long as five weeks. 2) Thoracic duct lymph samples obtained from severely burned rats contain a hemagglutinin specific for rat erythrocytes. This hemagglutinating factor has been identified as a 7S gamma globulin, and may constitute an immune response to altered autologous tissues.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1968.tb14753.x