Treatment of Cystinuria with α-Mercaptopropionylglycine: A Preliminary Report with Some Notes on Column Chromatography of Mercaptans

Summary In acute trials α-mercaptopropionylglycine (MPG) appears to be approximately as effective as D-penicillamine in lowering to safe levels the urinary cystine excretion by cystinurics. Analytical results show the mechanism of action to be the same. No side effects were seen here. Some new analy...

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Veröffentlicht in:	Proceedings of the Society for Experimental Biology and Medicine 1968-12, Vol.129 (3), p.927-932
1. Verfasser:	King, J. Stanton
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - therapeutic use Amino Acids - urine Chromatography Cysteine - urine Cystinuria - drug therapy Humans Taurine - urine
Online-Zugang:	Volltext
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Zusammenfassung:	Summary In acute trials α-mercaptopropionylglycine (MPG) appears to be approximately as effective as D-penicillamine in lowering to safe levels the urinary cystine excretion by cystinurics. Analytical results show the mechanism of action to be the same. No side effects were seen here. Some new analytical information on other mercaptans is reported, for comparison.
ISSN:	0037-9727 1535-3699
DOI:	10.3181/00379727-129-33461