Transformation of Human Lymphocytes: Inhibition by Homologous Alpha Globulin
An alpha globulin fraction prepared from normal human plasma by column chromatography prevents homologous lymphocyte transformation and the stimulation of DNA, and also protein synthesis induced by phytohemagglutinin and specific antigens. These observations support the concept of a normal circulati...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1968-03, Vol.159 (3820), p.1243-1244 |
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| container_end_page | 1244 |
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| container_issue | 3820 |
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| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 159 |
| creator | Cooperband, Sidney R. Bondevik, Helge Schmid, Karl Mannick, John A. |
| description | An alpha globulin fraction prepared from normal human plasma by column chromatography prevents homologous lymphocyte transformation and the stimulation of DNA, and also protein synthesis induced by phytohemagglutinin and specific antigens. These observations support the concept of a normal circulating immunosuppressant factor which prevents lymphoid cell proliferation. |
| doi_str_mv | 10.1126/science.159.3820.1243 |
| format | Article |
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These observations support the concept of a normal circulating immunosuppressant factor which prevents lymphoid cell proliferation.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>4179930</pmid><doi>10.1126/science.159.3820.1243</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1968-03, Vol.159 (3820), p.1243-1244 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_85064867 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
| subjects | Alpha globulins Alpha-Globulins - pharmacology Antibodies Blood plasma Blood Proteins - biosynthesis Cell culture techniques Cell Differentiation Culture Techniques Cultured cells Depression, Chemical Diphtheria Toxoid - pharmacology DNA DNA - biosynthesis Gene expression regulation Humans Lectins - antagonists & inhibitors Lymphocytes Lymphocytes - immunology Phosphorus Isotopes Phytohemagglutinins Serum Albumin, Bovine - antagonists & inhibitors Tetanus Toxoid - pharmacology Tuberculin |
| title | Transformation of Human Lymphocytes: Inhibition by Homologous Alpha Globulin |
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