Carcinostatic Activity of Several New Derivatives of Sulfonic Acid esters of Some Aminoglycols

Six new derivatives of sulfonic acid esters of aminoglycols were prepared and tested for their carcinostatic activity against Yoshida sarcoma. All the tested compounds showed strong cytomorphological effects on the tumor cells but not effective in prologation of life span of the tumor bearing animal...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1965/11/25, Vol.13(11), pp.1363-1365
Hauptverfasser:	Sakurai, Yoshio, El-Merzabani, Mahmoud M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Alcohols Animals Antineoplastic Agents Chemical Phenomena Chemistry Rats Sarcoma, Yoshida - drug therapy Sulfonic Acids - pharmacology
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Zusammenfassung:	Six new derivatives of sulfonic acid esters of aminoglycols were prepared and tested for their carcinostatic activity against Yoshida sarcoma. All the tested compounds showed strong cytomorphological effects on the tumor cells but not effective in prologation of life span of the tumor bearing animals.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.13.1363