An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid
Immunoelectrophoretic experiments using a rabbit antiserum to bovine CSF to develop the patterns have shown that a characteristic albumin and a γ-globulin exist in bovine CSF. Both proteins can also be demonstrated in saline extracts of calf brain. This finding suggests that certain as yet unknown n...
Gespeichert in:
| Veröffentlicht in: | The Journal of immunology (1950) 1965-10, Vol.95 (4), p.629-634 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 634 |
|---|---|
| container_issue | 4 |
| container_start_page | 629 |
| container_title | The Journal of immunology (1950) |
| container_volume | 95 |
| creator | MacPherson, C F Saffran, M |
| description | Immunoelectrophoretic experiments using a rabbit antiserum to bovine CSF to develop the patterns have shown that a characteristic albumin and a γ-globulin exist in bovine CSF. Both proteins can also be demonstrated in saline extracts of calf brain. This finding suggests that certain as yet unknown neurosecretory cells of the brain are the source of these proteins.
The bovine γc-globulin is analogous to the γc-globulin of human CSF in that it exists in two molecular forms with different electrophoretic mobilities but the same immunologic specificities.
From visual inspection of the immunoelectrophoretic patterns of CSF from immature and mature animals, it would appear that the CSF of the young animal contains more γc-globulin and less γG-globulin than the CSF of the adult. |
| doi_str_mv | 10.4049/jimmunol.95.4.629 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_85010599</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>85010599</sourcerecordid><originalsourceid>FETCH-LOGICAL-c339t-9d83e83c9dca17348b3bf974e2f6abb300666cbcd6c52ee8e6aa2df69de540f83</originalsourceid><addsrcrecordid>eNo9kEtLAzEAhIMotVZ_gAdhT952TTaPJsdSfFLwoueQZ01JdmuyK_jvXWn1NDDMDMMHwDWCDYFE3O1CSmPXx0bQhjSsFSdgjiiFNWOQnYI5hG1boyVbnoOLUnYQQgZbMgMzgignjM_By6qrVNRjCpN2ttqqlFS9jb0e42SZD5WVGVwOZQim6n2l-6_Qucq47HTuyz50KlY-jsFegjOvYnFXR12A94f7t_VTvXl9fF6vNrXBWAy1sBw7jo2wRqElJlxj7cWSuNYzpTWePjJmtLHM0NY57phSrfVMWEcJ9BwvwO1hd5_7z9GVQaZQjItRda4fi-QUIkiFmILoEDTT0ZKdl_scksrfEkH5y0_-8ZOCSiInflPn5jg-6uTsf-MIDP8ABWBvqQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>85010599</pqid></control><display><type>article</type><title>An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>MacPherson, C F ; Saffran, M</creator><creatorcontrib>MacPherson, C F ; Saffran, M</creatorcontrib><description>Immunoelectrophoretic experiments using a rabbit antiserum to bovine CSF to develop the patterns have shown that a characteristic albumin and a γ-globulin exist in bovine CSF. Both proteins can also be demonstrated in saline extracts of calf brain. This finding suggests that certain as yet unknown neurosecretory cells of the brain are the source of these proteins.
The bovine γc-globulin is analogous to the γc-globulin of human CSF in that it exists in two molecular forms with different electrophoretic mobilities but the same immunologic specificities.
From visual inspection of the immunoelectrophoretic patterns of CSF from immature and mature animals, it would appear that the CSF of the young animal contains more γc-globulin and less γG-globulin than the CSF of the adult.</description><identifier>ISSN: 0022-1767</identifier><identifier>EISSN: 1550-6606</identifier><identifier>DOI: 10.4049/jimmunol.95.4.629</identifier><identifier>PMID: 4158468</identifier><language>eng</language><publisher>United States</publisher><subject>Albumins ; Animals ; Cattle ; Cerebrospinal Fluid Proteins ; gamma-Globulins ; Immunochemistry ; Immunoelectrophoresis ; In Vitro Techniques</subject><ispartof>The Journal of immunology (1950), 1965-10, Vol.95 (4), p.629-634</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-9d83e83c9dca17348b3bf974e2f6abb300666cbcd6c52ee8e6aa2df69de540f83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4158468$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacPherson, C F</creatorcontrib><creatorcontrib>Saffran, M</creatorcontrib><title>An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid</title><title>The Journal of immunology (1950)</title><addtitle>J Immunol</addtitle><description>Immunoelectrophoretic experiments using a rabbit antiserum to bovine CSF to develop the patterns have shown that a characteristic albumin and a γ-globulin exist in bovine CSF. Both proteins can also be demonstrated in saline extracts of calf brain. This finding suggests that certain as yet unknown neurosecretory cells of the brain are the source of these proteins.
The bovine γc-globulin is analogous to the γc-globulin of human CSF in that it exists in two molecular forms with different electrophoretic mobilities but the same immunologic specificities.
From visual inspection of the immunoelectrophoretic patterns of CSF from immature and mature animals, it would appear that the CSF of the young animal contains more γc-globulin and less γG-globulin than the CSF of the adult.</description><subject>Albumins</subject><subject>Animals</subject><subject>Cattle</subject><subject>Cerebrospinal Fluid Proteins</subject><subject>gamma-Globulins</subject><subject>Immunochemistry</subject><subject>Immunoelectrophoresis</subject><subject>In Vitro Techniques</subject><issn>0022-1767</issn><issn>1550-6606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1965</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEAhIMotVZ_gAdhT952TTaPJsdSfFLwoueQZ01JdmuyK_jvXWn1NDDMDMMHwDWCDYFE3O1CSmPXx0bQhjSsFSdgjiiFNWOQnYI5hG1boyVbnoOLUnYQQgZbMgMzgignjM_By6qrVNRjCpN2ttqqlFS9jb0e42SZD5WVGVwOZQim6n2l-6_Qucq47HTuyz50KlY-jsFegjOvYnFXR12A94f7t_VTvXl9fF6vNrXBWAy1sBw7jo2wRqElJlxj7cWSuNYzpTWePjJmtLHM0NY57phSrfVMWEcJ9BwvwO1hd5_7z9GVQaZQjItRda4fi-QUIkiFmILoEDTT0ZKdl_scksrfEkH5y0_-8ZOCSiInflPn5jg-6uTsf-MIDP8ABWBvqQ</recordid><startdate>196510</startdate><enddate>196510</enddate><creator>MacPherson, C F</creator><creator>Saffran, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196510</creationdate><title>An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid</title><author>MacPherson, C F ; Saffran, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-9d83e83c9dca17348b3bf974e2f6abb300666cbcd6c52ee8e6aa2df69de540f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1965</creationdate><topic>Albumins</topic><topic>Animals</topic><topic>Cattle</topic><topic>Cerebrospinal Fluid Proteins</topic><topic>gamma-Globulins</topic><topic>Immunochemistry</topic><topic>Immunoelectrophoresis</topic><topic>In Vitro Techniques</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MacPherson, C F</creatorcontrib><creatorcontrib>Saffran, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of immunology (1950)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MacPherson, C F</au><au>Saffran, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid</atitle><jtitle>The Journal of immunology (1950)</jtitle><addtitle>J Immunol</addtitle><date>1965-10</date><risdate>1965</risdate><volume>95</volume><issue>4</issue><spage>629</spage><epage>634</epage><pages>629-634</pages><issn>0022-1767</issn><eissn>1550-6606</eissn><abstract>Immunoelectrophoretic experiments using a rabbit antiserum to bovine CSF to develop the patterns have shown that a characteristic albumin and a γ-globulin exist in bovine CSF. Both proteins can also be demonstrated in saline extracts of calf brain. This finding suggests that certain as yet unknown neurosecretory cells of the brain are the source of these proteins.
The bovine γc-globulin is analogous to the γc-globulin of human CSF in that it exists in two molecular forms with different electrophoretic mobilities but the same immunologic specificities.
From visual inspection of the immunoelectrophoretic patterns of CSF from immature and mature animals, it would appear that the CSF of the young animal contains more γc-globulin and less γG-globulin than the CSF of the adult.</abstract><cop>United States</cop><pmid>4158468</pmid><doi>10.4049/jimmunol.95.4.629</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1767 |
| ispartof | The Journal of immunology (1950), 1965-10, Vol.95 (4), p.629-634 |
| issn | 0022-1767 1550-6606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_85010599 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Albumins Animals Cattle Cerebrospinal Fluid Proteins gamma-Globulins Immunochemistry Immunoelectrophoresis In Vitro Techniques |
| title | An albumin and gamma-globulin characteristic of bovine cerebrospinal fluid |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T01%3A53%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20albumin%20and%20gamma-globulin%20characteristic%20of%20bovine%20cerebrospinal%20fluid&rft.jtitle=The%20Journal%20of%20immunology%20(1950)&rft.au=MacPherson,%20C%20F&rft.date=1965-10&rft.volume=95&rft.issue=4&rft.spage=629&rft.epage=634&rft.pages=629-634&rft.issn=0022-1767&rft.eissn=1550-6606&rft_id=info:doi/10.4049/jimmunol.95.4.629&rft_dat=%3Cproquest_cross%3E85010599%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=85010599&rft_id=info:pmid/4158468&rfr_iscdi=true |