Tricarboxylic Acid Cycle in Wound Healing by Granulation.

Summary The existence of all the enzymes of Tricarboxylic Acid Cycle in granulation tissue was demonstrated by the increase in oxygen consumption in the presence of appropriate intermediates. No effect was observed with added glucose and values for aerobic and anaerobic lactic acid production by 10-...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1965-08, Vol.119 (4), p.1011-1014
Hauptverfasser:	Nowinski, Wiktor W., Blocker, Truman G., Ohkubo, Tatsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Citrates - metabolism Citric Acid Cycle Fumarates - metabolism Glucose - metabolism Granulation Tissue - metabolism Hexosephosphates - metabolism In Vitro Techniques Ketoglutaric Acids - metabolism Lactates - metabolism Malates - metabolism Oxaloacetates - metabolism Oxygen Consumption Pyruvates - metabolism Rabbits Succinates - metabolism
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Zusammenfassung:	Summary The existence of all the enzymes of Tricarboxylic Acid Cycle in granulation tissue was demonstrated by the increase in oxygen consumption in the presence of appropriate intermediates. No effect was observed with added glucose and values for aerobic and anaerobic lactic acid production by 10-day-old granulation tissue were identical. These results suggest the absence of Pasteur effect at this stage of wound healing.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-119-30362