Excess Iodide Ingestion and Thyroid Function in Chicks

Summary The effect of excess ioide in the drinking water on the thyroid function of chicks has been studied. There was no evidence of goiter production in four breeds of chicks fed up to 0.5% (w/v) KI in water for periods of up to six months. There was some evidence in acute experiments to suggest a...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1968-11, Vol.129 (2), p.370-373
Hauptverfasser:	Mayberry, William E., Hockert, Thomas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chickens Injections, Intraperitoneal Injections, Subcutaneous Iodides - pharmacology Iodine Radioisotopes Methods Models, Biological Organ Size Oxygen Consumption Potassium Iodide - pharmacology Thyroid Function Tests Thyroid Gland - drug effects Thyroxine - antagonists & inhibitors Thyroxine - biosynthesis Thyroxine - blood
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Zusammenfassung:	Summary The effect of excess ioide in the drinking water on the thyroid function of chicks has been studied. There was no evidence of goiter production in four breeds of chicks fed up to 0.5% (w/v) KI in water for periods of up to six months. There was some evidence in acute experiments to suggest a temporary Wolff-Chaikoff effect with excess iodides. Components of thyroid hydrolysates were not different in iodide-treated chicks as compared to chicks not given excess iodide.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-129-33323