Determination of Antipyrine in Combinations with Other Drugs
Antipyrine in pharmaceutical preparations is determined by isolation from an ether solution on a Celite–ferric chloride partition column. It is eluted free of ferric ion with chloroform and its concentration in the eluate is measured spectrophotometrically. None of the components of the usual drug c...
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Veröffentlicht in: | Journal of pharmaceutical sciences 1965-04, Vol.54 (4), p.636-638 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Antipyrine in pharmaceutical preparations is determined by isolation from an ether solution on a Celite–ferric chloride partition column. It is eluted free of ferric ion with chloroform and its concentration in the eluate is measured spectrophotometrically. None of the components of the usual drug combinations interfere. With slight modification, the concurrent determination of components such as caffeine, benzocaine, salicylic acid, and iodopyrine, can be made. |
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ISSN: | 0022-3549 1520-6017 |
DOI: | 10.1002/jps.2600540432 |