Periodontal regeneration using engineered bone marrow mesenchymal stromal cells

Abstract Regeneration of lost periodontium is a challenge in that both hard (alveolar bone, cementum) and soft (periodontal ligament) connective tissues need to be restored to their original architecture. Bone marrow mesenchymal stromal cells (BM-MSCs) appear to be an attractive candidate for connec...

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Veröffentlicht in:	Biomaterials 2010-11, Vol.31 (33), p.8574-8582
Hauptverfasser:	Yang, Yi, Rossi, Fabio M.V, Putnins, Edward E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Adult bone marrow mesenchymal stromal cells Advanced Basic Science Animals Beads Bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Bones Cementogenesis - drug effects Cements Connective tissue Dental Cementum - cytology Dental Cementum - drug effects Dentistry Gelatin - pharmacology Green Fluorescent Proteins - metabolism In vivo Isoenzymes - metabolism Ligaments Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Microspheres Osteocalcin - metabolism Osteogenesis - drug effects Periodontal Ligament - cytology Periodontal Ligament - drug effects Periodontal Ligament - growth & development Periodontal regeneration Periodontium - drug effects Periodontium - pathology Periodontium - physiology Rats Rats, Sprague-Dawley Regeneration Regeneration - drug effects Regeneration - physiology Restoration Stromal Cells - cytology Stromal Cells - drug effects Tartrate-Resistant Acid Phosphatase Tissue engineering Wound Healing - drug effects
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