Pyrrolo [2,3-d]Pyrimidines

Pyrrolo [2,3-d]Pyrimidines

The synthesis of a series of 4-alkylamino-7-methyl analogs of tubercidin from 4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine is described.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of pharmaceutical sciences 1968-09, Vol.57 (9), p.1616-1619
1. Verfasser: Hammer, Richard H.
Format: Artikel
Sprache:eng
Schlagworte:
3-d]pyrimidines-synthesis
Antineoplastic Agents - chemical synthesis
Cytotoxicity screening-tubercidin analogs
Magnetic Resonance Spectroscopy
NMR spectroscopy-identity
Nucleosides - chemical synthesis
pKa values-titration
Proton magnetic resonance-identity
Pyrimidines - chemical synthesis
Pyrroles - chemical synthesis
Pyrrolo
Pyrrolo[2,3-d]pyrimidines—synthesis
Spectrophotometry
TLC-separation
Tubercidin analogs
UV spectrophotometry-identity
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Beschreibung
Zusammenfassung:The synthesis of a series of 4-alkylamino-7-methyl analogs of tubercidin from 4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine is described.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600570934