Effect of Acid Treatment on the Immunosuppressive Properties of Anti-lymphocytic IgG

THE abolition of the complement binding activity of IgG globulin molecules by exposure to low p Hs (refs. 1 and 2) has prompted us to investigate the effect of acid-treated anti-lymphocytic IgG on humoral and cell mediated immune responses in the rat. These studies form part of a larger investigatio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1968-05, Vol.218 (5143), p.771-773
Hauptverfasser:	ANDERSON, N. F, JAMES, K, WOODRUFF, M. F. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic - pharmacology Antibody Formation Chromatography, Gel Female Humanities and Social Sciences Hydrogen-Ion Concentration Immunoelectrophoresis Immunosuppressive Agents - pharmacology letter Lymphocytes Male multidisciplinary Rats Science Science (multidisciplinary) Skin Transplantation Transplantation, Homologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	THE abolition of the complement binding activity of IgG globulin molecules by exposure to low p Hs (refs. 1 and 2) has prompted us to investigate the effect of acid-treated anti-lymphocytic IgG on humoral and cell mediated immune responses in the rat. These studies form part of a larger investigation aimed at elucidating the mode of action of anti-lymphocytic serum and developing less toxic products for therapeutic use.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/218771a0