Chromosome region 2p25 is linked and associated with type 1 diabetes in Colombia

Type 1 diabetes (T1D) is a heterogeneous disorder which involves both genetic and environmental factors. Among the environmental factors, viral and milk proteins have been suggested as important risk factors for triggering the disease. Among genetic factors, more than 20 loci have been identied in t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of genetics 2010-12, Vol.89 (4), p.457-461
Hauptverfasser:	Pineda-Trujilo, Nicolas, Uribe, Federico, Montoya, Fabiola, Alfaro, Juan-Manuel, Latorre, Guillermo, Villegas, Alberto, Ceron, Javier, Perez, Andres-Felipe, Ospina, Mariano, Naranjo, Andres, Serrano, Abel, Duque, Ivan, Castrillon, Debora, Abad, Alberto, Bedoya, Gabriel, Balthazar, Vital, Ruiz-Linares, Andres
Format:	Artikel
Sprache:	eng
Schlagworte:	Age of Onset Alleles Animal Genetics and Genomics Autoantigens - genetics Biomedical and Life Sciences Chromosomes Chromosomes, Human, Pair 2 Colombia Diabetes Diabetes Mellitus, Type 1 - genetics Evolutionary Biology Female Gene Frequency Genes, Dominant Genetic Linkage Genetic Loci Genetic Markers Genetic Predisposition to Disease Genetics Haplotypes Humans Iodide Peroxidase - genetics Iron-Binding Proteins - genetics Life Sciences Lod Score Male Microbial Genetics and Genomics Nuclear Family Pedigree Penetrance Physical Chromosome Mapping Plant Genetics and Genomics Research Note Risk factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Type 1 diabetes (T1D) is a heterogeneous disorder which involves both genetic and environmental factors. Among the environmental factors, viral and milk proteins have been suggested as important risk factors for triggering the disease. Among genetic factors, more than 20 loci have been identied in the susceptibility for T1D. Pineda-Trujilo et al report progress on ne mapping of a novel locus on 2p25, which was initially identied in a large family with T1D from Antioquia, Colombia.
ISSN:	0022-1333 0973-7731
DOI:	10.1007/s12041-010-0064-4