Acid-Labile Carbon Dioxide in Muscle: Its Nature and Relationship to Intracellular pH.

Summary A portion of the acid-labile CO2 in alkaline extracts of rat muscle is not precipitable by BaCl2. Carbonate added to an extract that has been acidified, freed of CO2 by evacuation, and realkalinized is only partially precipitated. It is concluded that barium solubility is the effect of some...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1967-07, Vol.125 (3), p.972-974
Hauptverfasser:	Butler, Thomas C., Poole, Doris T., Waddell, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - pharmacology Animals Carbon Dioxide - metabolism Hydrogen-Ion Concentration Hydroxides - pharmacology Intracellular Space - physiology Muscle, Skeletal - physiology Potassium Compounds - pharmacology Rats Serum Albumin, Bovine - pharmacology
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Zusammenfassung:	Summary A portion of the acid-labile CO2 in alkaline extracts of rat muscle is not precipitable by BaCl2. Carbonate added to an extract that has been acidified, freed of CO2 by evacuation, and realkalinized is only partially precipitated. It is concluded that barium solubility is the effect of some substance in the muscle extract in inhibiting crystallization of a limited amount of BaCO3. Calculation of intracellular pH from total acid-labile CO2 appears valid.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-125-32252