Increased survival of xenogeneic tumor in thymectomized hosts

Increased survival of xenogeneic tumor in thymectomized hosts

An amelanotic hamster melanoma was successfully transplanted in 43 of 45 neonatally thymectomized rats. The tumors remained viable longer than fourteen days in 22 of the rats but all were rejected before becoming fatal. Tumors growing in thymectomized rats could be transplanted successfully to other...

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Veröffentlicht in:The Journal of surgical research 1968, Vol.8 (1), p.7-9
Hauptverfasser: Grogan, James B., Hardy, James D.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Animals, Newborn
Antigens, Heterophile
Cricetinae
Melanoma - pathology
Necrosis
Neoplasm Transplantation
Neoplasms, Experimental
Rats
Thymectomy
Thymus Gland - physiology
Transplantation Immunology
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Beschreibung
Zusammenfassung:An amelanotic hamster melanoma was successfully transplanted in 43 of 45 neonatally thymectomized rats. The tumors remained viable longer than fourteen days in 22 of the rats but all were rejected before becoming fatal. Tumors growing in thymectomized rats could be transplanted successfully to other thymectomized rats and to hamsters, but not to normal rats.
ISSN:0022-4804
1095-8673
DOI:10.1016/0022-4804(68)90125-X