Concentrations of Metabolic Intermediates in Kidneys of Rats with Metabolic Acidosis

GOODMAN et al. 1 have shown that there is enhanced renal gluconeogenesis in the rat with chronic metabolic acidosis. The enhancement of renal gluconeogenesis with glut-amine, glutamate, α-ketoglutarate and oxaloacetate, but not with fructose or glycerol as substrates, led to the tentative conclusion...

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