PROTECTIVE EFFECT OF ROYAL JELLY ON SOME BIOCHEMICAL PARAMETERS IN CADMIUM-TREATED ALBINO MICE

In the present study, the protective role of Royal Jelly (RJ) on cadmium-induced toxicity in albino mice was investigated. The mice were divided into six groups. The control group received tap water, mice of treatment groups received 2 mg/kg body weight cadmium and two different doses of RJ (100 and 250 mg/kg b. wt) for 6 weeks by oral gavage. The levels of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), blood urea nitrogen (BUN) and creatinine were evaluated. In addition, histopathological changes in liver and kidneys were investigated. Serum levels of AST, ALT, ALP, BUN and creatinine in mice receiving cadmium alone significantly increased compared to the other groups (p