Platelets prevent acute hepatitis induced by anti-fas antibody

Background and Aim: Platelets provide many functions in the body, especially to the liver. The purpose of this study is to investigate the effect of thrombocytosis with acute hepatitis induced by anti‐Fas antibody and its mechanism. Methods: Acute hepatitis was induced by administration of anti‐Fa...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2011-02, Vol.26 (2), p.348-355
Hauptverfasser:	Hisakura, Katsuji, Murata, Soichiro, Takahashi, Kazuhiro, Matsuo, Ryota, Pak, Sugiru, Ikeda, Naoya, Kawasaki, Takuya, Kohno, Keisuke, Myronovych, Andriy, Nakano, Yoritaka, Ikeda, Osamu, Watanabe, Motonobu, Ohkohchi, Nobuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute hepatitis AKT protein Alanine transaminase Alanine Transaminase - blood Animals Antibodies Apoptosis Apoptosis - drug effects Apoptosis Regulatory Proteins - metabolism Bcl-x protein Biological and medical sciences Caspase-3 Cell Line Disease Models, Animal Endothelial cells Endothelial Cells - drug effects Endothelial Cells - metabolism Endothelial Cells - pathology fas Receptor - immunology Gastroenterology. Liver. Pancreas. Abdomen Hemorrhage Hepatitis Hepatitis - blood Hepatitis - immunology Hepatitis - pathology Hepatitis - prevention & control hepatocyte Hepatocytes Hepatocytes - drug effects Hepatocytes - metabolism Hepatocytes - pathology In Situ Nick-End Labeling Liver Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Mice Mice, Inbred C57BL Necrosis Other diseases. Semiology Phosphorylation Platelet Count Platelets Polyethylene Glycols Recombinant Proteins Staurosporine Staurosporine - pharmacology Thrombocytopenia - blood Thrombocytopenia - chemically induced Thrombocytopenia - pathology thrombocytosis Thrombocytosis - blood Thrombocytosis - chemically induced Thrombocytosis - pathology Thrombopoiesis Thrombopoietin Time Factors
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