Selective Vagotomy of the Parietal Cell Mass Preserving Innervation of the Undrained Antrum: A preliminary report of results in patients with duodenal ulcer

Selective vagotomy of the parietal cell mass sparing the innervation of the undrained antrum in treatment of patients with hyperacidity and duodenal ulcer is described. Postoperative gastric emptying is normal. Incidence of dumping is nil. Spontaneous acid secretion and insulin-provoked acid secretion was reduced by about 90%. Pentapeptide-provoked acid secretion was reduced by about 60%. Early results are promising in that ulcer pain and acid regurgitation have been completely relieved, but the follow-up period is still too short for further evaluation.