Efficacy of induced luteinizing hormone surge after “trigger” with gonadotropin-releasing hormone agonist

The magnitude of the LH surge after GnRH agonist “trigger” was correlated with oocyte yield and maturity and was suboptimal in approximately half of the cycles. A modest reduction in oocyte yield and maturity was observed when the serum level of LH 12 hours after GnRH agonist trigger was less than the median value (52 IU/L), and a dramatic reduction in yield and maturity was observed when that level was less than 12 IU/L.