The C-Alkyl-aminomethylation of 3-Pyridazinol 1-Oxide Derivatives. I

The C-Alkyl-aminomethylation of 3-Pyridazinol 1-Oxide Derivatives. I

The Mannich reaction of 3-pyridazinol 1-oxide using morpholine, piperidine, or dimethylamine gave the corresponding 6-alkylaminomethyl-3-pyridazinol 1-oxides which were also synthesized from 3-methoxy-6-chloromethylpyridazine.

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1967/08/25, Vol.15(8), pp.1172-1177
Hauptverfasser: Okusa, Genzo, Kamiya, Shozo, Itai, Takanobu
Format: Artikel
Sprache:eng
Schlagworte:
Methylation
Pyridazines
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Zusammenfassung:The Mannich reaction of 3-pyridazinol 1-oxide using morpholine, piperidine, or dimethylamine gave the corresponding 6-alkylaminomethyl-3-pyridazinol 1-oxides which were also synthesized from 3-methoxy-6-chloromethylpyridazine.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.15.1172