Human Placental Lactogen and Insulin-Blood Glucose Homeostasis

Human Placental Lactogen and Insulin-Blood Glucose Homeostasis

Normal pregnant women at or near term were tested by a double IV glucose loading procedure. Serum immunoreactive insulin, placental lactogenic hormone (HPL) and blood glucose levels were determined sequentially for 3 hr. HPL was found to decrease significantly during the first 30 min of the test. It...

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Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 1970-08, Vol.36 (2), p.233-237
Hauptverfasser: BURT, RICHARD L., LEAKE, NORMAN H., RHYNE, A. LEONARD
Format: Artikel
Sprache:eng
Schlagworte:
Blood Glucose - analysis
Feedback
Female
Glucose Tolerance Test
Growth Hormone - blood
Growth Hormone - metabolism
Homeostasis
Humans
Immune Sera
Insulin - blood
Insulin - metabolism
Insulin Secretion
Maternal-Fetal Exchange
Placental Hormones
Placental Lactogen
Pregnancy
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Beschreibung
Zusammenfassung:Normal pregnant women at or near term were tested by a double IV glucose loading procedure. Serum immunoreactive insulin, placental lactogenic hormone (HPL) and blood glucose levels were determined sequentially for 3 hr. HPL was found to decrease significantly during the first 30 min of the test. It is suggested that HPL may relate to glucose homeostasis in pregnancy, the negative feedback being of fetal origin.
ISSN:0029-7844
1873-233X