Pulmonary Surfactant and Evolution of the Lungs

Pulmonary Surfactant and Evolution of the Lungs

Pulmonary surfactant has been looked for and found in 11 representatives of four vertebrate classes. The amount of surfactant, estimated by quantitative spreading as a surface film, correlates well with alveolar surface area and with the amount of saturated, mainly dipalmitoyl, phosphatidylcholine i...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1970-08, Vol.169 (3945), p.603-604
Hauptverfasser: Clements, John A., Nellenbogen, Jean, Trahan, Harold J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anura
Biological Evolution
Caniformia
Cattle
Chickens
Dogs
Guinea Pigs
Lipids
Lipoproteins - analysis
Lung - physiology
Lungs
Mice
Phosphatidylcholines
Phosphatidylcholines - analysis
Phospholipids
Phospholipids - analysis
Pulmonary alveoli
Pulmonary Alveoli - analysis
Pulmonary surfactants
Rabbits
Rats
Surface areas
Surface Properties
Surface-Active Agents - analysis
Surfactants
Turtles
Vertebrates
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Beschreibung
Zusammenfassung:Pulmonary surfactant has been looked for and found in 11 representatives of four vertebrate classes. The amount of surfactant, estimated by quantitative spreading as a surface film, correlates well with alveolar surface area and with the amount of saturated, mainly dipalmitoyl, phosphatidylcholine in the lung parenchyma. The quantities of other phospholipids do not correlate well with alveolar surface area.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.169.3945.603