Substrates of Kinin-releasing Enzymes isolated from Horse Plasma

KININOGEN has been isolated from horse plasma 1 , bovine plasma 2–4 , human plasma 5 and rabbit plasma 6 . Several authors, however, have shown that plasma contains at least two kininogens with affinities for different releasing enzymes 7–10 . Recently, Jacobsen 11 detected the presence of two kininogens in human, dog and rabbit plasma—one which forms kinin with plasma kallikrein and another which forms kinin only when incubated with glandular kallikrein.