Radiosensitization of endometrial adenocarcinoma by means of medroxyprogesterone

Hormone dependency and radiosensitivity of endometrial adenocarcinoma are studied. Pathologic data are compared for hysterectomy or curettement specimens obtained after curietherapy, only after curietherapy is preceded by administration of medroxyprogesterone. Destruction of adenocarcinoma by curietherapy seems to be enhanced by means of medroxyprogesterone. These data suggest phenomena of radiosensitization characterized by definite histologic transformations.