Ferrioxamine Iron in Rabbit Reticulocyte Heme Synthesis

Ferrioxamine B, a naturally occurring sideramine, serves as an iron transport agent and iron donor for heme synthesis in micro organisms. It is unable to effectively replace transferrin in iron delivery for rabbit reticulocyte hemoglobin formation.

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Bibliographische Detailangaben
Veröffentlicht in:	Blood 1970-04, Vol.35 (4), p.493-495
Hauptverfasser:	Gerlanc, M.D., Zapolski, E.J., Rubin, M., Princiotto, J.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Animals Biological Transport Cell Membrane Cell Membrane Permeability Deferoxamine - metabolism Deferoxamine - pharmacology Deferoxamine - therapeutic use Heme - biosynthesis Hemochromatosis - drug therapy Iron - blood Iron Chelating Agents - metabolism Iron Chelating Agents - pharmacology Iron Isotopes Rabbits Reticulocytes - drug effects Reticulocytes - metabolism Transferrin
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Beschreibung
Zusammenfassung:	Ferrioxamine B, a naturally occurring sideramine, serves as an iron transport agent and iron donor for heme synthesis in micro organisms. It is unable to effectively replace transferrin in iron delivery for rabbit reticulocyte hemoglobin formation.
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood.V35.4.493.493