INCIDENCE OF INFLUENZA VIRUS INFECTION IN EARLY INFANCY: A PROSPECTIVE STUDY IN SOUTH ASIA

We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases...

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Veröffentlicht in:	The Pediatric infectious disease journal 2011-02, Vol.30 (2), p.170-173
Hauptverfasser:	HENKLE, Emily, STEINHOFF, Mark C, OMER, Saad B, ROY, Eliza, ARIFEEN, Shams E, RAQIB, Rubhana, MCNEAL, Monica, BREIMAN, Robert F, MOSS, William J, ZAMAN, K
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Sprache:	eng
Schlagworte:	Antibodies, Viral - blood Asia - epidemiology Biological and medical sciences Female Hemagglutination Inhibition Tests Human viral diseases Humans Incidence Infant Infant, Newborn Infectious diseases Influenza, Human - epidemiology Male Medical sciences Prospective Studies Seroepidemiologic Studies Viral diseases Viral diseases of the respiratory system and ent viral diseases
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container_title	The Pediatric infectious disease journal
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creator	HENKLE, Emily STEINHOFF, Mark C OMER, Saad B ROY, Eliza ARIFEEN, Shams E RAQIB, Rubhana MCNEAL, Monica BREIMAN, Robert F MOSS, William J ZAMAN, K
description	We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.
doi_str_mv	10.1097/INF.0b013e3181f63c39
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subjects	Antibodies, Viral - blood Asia - epidemiology Biological and medical sciences Female Hemagglutination Inhibition Tests Human viral diseases Humans Incidence Infant Infant, Newborn Infectious diseases Influenza, Human - epidemiology Male Medical sciences Prospective Studies Seroepidemiologic Studies Viral diseases Viral diseases of the respiratory system and ent viral diseases
title	INCIDENCE OF INFLUENZA VIRUS INFECTION IN EARLY INFANCY: A PROSPECTIVE STUDY IN SOUTH ASIA
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