Heterologous Antilymphocyte Globulin: Studies in vitro

Heterologous Antilymphocyte Globulin: Studies in vitro

Incubation of dog-lymphocyte cultures with globulin from antiserum to lymphocytes resulted in a greater percentage of transformed cells than incubation with phytohemagglutinin. Viability counts demonstrated that this globulin and phytohemagglutinin had approximately equal degrees of cytotoxicity.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1967-07, Vol.157 (3787), p.441-441
Hauptverfasser: Humphrey, Loren J., Kauffman, H. Myron, Dunn, Ellis
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antiserum
Blasts
Culture Techniques
Cultured cells
Dogs
Globulins
Homologous transplantation
Horses
Immune response
Immune Sera
Lectins - pharmacology
Lymphocytes
Lymphocytes - drug effects
Serum Globulins - pharmacology
Viability
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Beschreibung
Zusammenfassung:Incubation of dog-lymphocyte cultures with globulin from antiserum to lymphocytes resulted in a greater percentage of transformed cells than incubation with phytohemagglutinin. Viability counts demonstrated that this globulin and phytohemagglutinin had approximately equal degrees of cytotoxicity.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.157.3787.441