Genetics of Phenylketonuria: Heterozygosity for phenylketonuria

Genetics of Phenylketonuria: Heterozygosity for phenylketonuria

The first article deals with the problem of using the response to injected phenylalanine to determine whether or not the subject is heterozygous for phenylketonuria. The second article suggests a third allele on the phenylketonuria locus, the corresponding enzyme having a higher affinity for phenyla...

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Veröffentlicht in:Nature (London) 1967-03, Vol.213 (5079), p.882-883
Hauptverfasser: WOOLF, L. I, CRANSTON, W. I, GOODWIN, B. L
Format: Artikel
Sprache:eng
Schlagworte:
Cytogenetics
Female
Humanities and Social Sciences
Humans
Male
multidisciplinary
Phenylalanine - blood
Phenylalanine - urine
Phenylketonurias - genetics
Science
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Zusammenfassung:The first article deals with the problem of using the response to injected phenylalanine to determine whether or not the subject is heterozygous for phenylketonuria. The second article suggests a third allele on the phenylketonuria locus, the corresponding enzyme having a higher affinity for phenylalanine than has the “normal” enzyme.
ISSN:0028-0836
1476-4687
DOI:10.1038/213882a0