Effect of furosemide on glucose metabolism
The administration of furosemide, a benzothiadiazine analogue, to rats results in elevation of the initial and 2-hour postglucose loading blood glucose levels. Furosemide given to rats causes a decrease in the rate of glucose utilization by their adipose tissue in vitro. Furosemide added directly to...
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| Veröffentlicht in: | Metabolism, clinical and experimental clinical and experimental, 1967-06, Vol.16 (6), p.532-536 |
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| container_end_page | 536 |
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| container_issue | 6 |
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| container_title | Metabolism, clinical and experimental |
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| creator | Weller, John M. Borondy, Maria |
| description | The administration of furosemide, a benzothiadiazine analogue, to rats results in elevation of the initial and 2-hour postglucose loading blood glucose levels. Furosemide given to rats causes a decrease in the rate of glucose utilization by their adipose tissue in vitro. Furosemide added directly to the incubational medium also decreases the rate of glucose utilization of normal rats' fat tissue in vitro. These effects of furosemide are similar to those produced by chlorothiazide and other benzothiadiazine compounds. |
| doi_str_mv | 10.1016/0026-0495(67)90083-2 |
| format | Article |
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Furosemide given to rats causes a decrease in the rate of glucose utilization by their adipose tissue in vitro. Furosemide added directly to the incubational medium also decreases the rate of glucose utilization of normal rats' fat tissue in vitro. 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Furosemide given to rats causes a decrease in the rate of glucose utilization by their adipose tissue in vitro. Furosemide added directly to the incubational medium also decreases the rate of glucose utilization of normal rats' fat tissue in vitro. These effects of furosemide are similar to those produced by chlorothiazide and other benzothiadiazine compounds.</description><subject>Adipose Tissue - drug effects</subject><subject>Adipose Tissue - metabolism</subject><subject>Animals</subject><subject>Blood Glucose</subject><subject>Chlorothiazide - pharmacology</subject><subject>Furosemide - pharmacology</subject><subject>Glucose - metabolism</subject><subject>Glucose Tolerance Test</subject><subject>Hydrochlorothiazide - pharmacology</subject><subject>In Vitro Techniques</subject><subject>Male</subject><subject>Rats</subject><issn>0026-0495</issn><issn>1532-8600</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UEtLxDAQDqKs6-o_UOhJVKhOHk2TiyDL-oAFL3oObTKRSLtdm1bw35t1lz16GobvMfN9hJxTuKVA5R0AkzkIXVzJ8loDKJ6zAzKlBWe5kgCHZLqnHJOTGD8BoCyVnJCJBFYyTafkZuE92iHrfObHvovYBodZt8o-mtGmNWtxqOquCbE9JUe-aiKe7eaMvD8u3ubP-fL16WX-sMytAD7ktZBWIQr0TmllqaUIjjnUQlZSi9pxzZzX1DPBGRMWla-A1yVVFAteeD4jl1vfdd99jRgH04ZosWmqFXZjNEoIJZmgiSi2RJsejz16s-5DW_U_hoLZVGQ2-c0mv5Gl-avIsCS72PmPdYtuL9p1kvD7LY4p5HfA3kQbcGXRhT5VZVwX_j_wC4vUdDg</recordid><startdate>196706</startdate><enddate>196706</enddate><creator>Weller, John M.</creator><creator>Borondy, Maria</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196706</creationdate><title>Effect of furosemide on glucose metabolism</title><author>Weller, John M. ; Borondy, Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-b46c8ee4efd898c1c1e0d2de946a694bd392df91f243224ce8fa03b7181e535f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Adipose Tissue - drug effects</topic><topic>Adipose Tissue - metabolism</topic><topic>Animals</topic><topic>Blood Glucose</topic><topic>Chlorothiazide - pharmacology</topic><topic>Furosemide - pharmacology</topic><topic>Glucose - metabolism</topic><topic>Glucose Tolerance Test</topic><topic>Hydrochlorothiazide - pharmacology</topic><topic>In Vitro Techniques</topic><topic>Male</topic><topic>Rats</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weller, John M.</creatorcontrib><creatorcontrib>Borondy, Maria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Metabolism, clinical and experimental</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weller, John M.</au><au>Borondy, Maria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of furosemide on glucose metabolism</atitle><jtitle>Metabolism, clinical and experimental</jtitle><addtitle>Metabolism</addtitle><date>1967-06</date><risdate>1967</risdate><volume>16</volume><issue>6</issue><spage>532</spage><epage>536</epage><pages>532-536</pages><issn>0026-0495</issn><eissn>1532-8600</eissn><abstract>The administration of furosemide, a benzothiadiazine analogue, to rats results in elevation of the initial and 2-hour postglucose loading blood glucose levels. 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| ispartof | Metabolism, clinical and experimental, 1967-06, Vol.16 (6), p.532-536 |
| issn | 0026-0495 1532-8600 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84486241 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Blood Glucose Chlorothiazide - pharmacology Furosemide - pharmacology Glucose - metabolism Glucose Tolerance Test Hydrochlorothiazide - pharmacology In Vitro Techniques Male Rats |
| title | Effect of furosemide on glucose metabolism |
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