Histochemical studies of steroid 3β-ol dehydrogenases of the human ovaries

The activity of steroid 3β-ol dehydrogenase and glucose-6-phosphate in normal and pathologic human ovaries was studied using seven kinds of steroids as the substrate. In theca- and granulosa-lutein cells of the corpus luteum, no correlation was found between the distributions of glucose-6-phosphate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of obstetrics and gynecology 1967-05, Vol.98 (1), p.107-115
Hauptverfasser:	Taki, Ichiro, Iijima, Hiroshi, Uetsuki, Masayo, Hamanaka, Nobuaki, Morishita, Masaaki, Mori, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Choriocarcinoma - metabolism Corpus Luteum - enzymology Cysts - metabolism Female Glucosephosphate Dehydrogenase - metabolism Histocytochemistry Humans Ovarian Diseases - metabolism Ovarian Follicle - enzymology Ovarian Neoplasms - metabolism Ovary - enzymology Oxidoreductases - metabolism Placenta - enzymology Pregnancy Trophoblastic Neoplasms - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The activity of steroid 3β-ol dehydrogenase and glucose-6-phosphate in normal and pathologic human ovaries was studied using seven kinds of steroids as the substrate. In theca- and granulosa-lutein cells of the corpus luteum, no correlation was found between the distributions of glucose-6-phosphate and steroid 3β-ol dehydrogenases. The activity of both enzymes showed similar distribution and intensity in normal follicle and cystic follicle of the polycystic ovary. An intense steroid dehydrogenase activity for androstane-3β-ol, 17-one and 5-androstene-3β-ol, 17-one in a luteinizing cyst associated with a chorionic tumor was suggestive of an abnormal steroid metabolism in the ovary.
ISSN:	0002-9378 1097-6868
DOI:	10.1016/0002-9378(67)90139-1