Synaptic Noise as a Source of Variability in the Interval between Action Potentials

Synaptic Noise as a Source of Variability in the Interval between Action Potentials

The source of variability in the interval between action potentials has been identified in a class of cat spinal motoneurons. The observed random fluctuations in membrane potential (synaptic noise) together with an empirical description of spike generation accurately predict the statistical structur...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1967-02, Vol.155 (3764), p.842-844
Hauptverfasser: Calvin, William H., Stevens, Charles F.
Format: Artikel
Sprache:eng
Schlagworte:
Action Potentials
Animals
Cats
Electric potential
Electrophysiology
Histograms
Membrane potential
Membrane Potentials
Modeling
Motor Neurons - physiology
Musical intervals
Neurons
Noise prediction
Signal noise
Spinal Cord - physiology
Synapses - physiology
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Beschreibung
Zusammenfassung:The source of variability in the interval between action potentials has been identified in a class of cat spinal motoneurons. The observed random fluctuations in membrane potential (synaptic noise) together with an empirical description of spike generation accurately predict the statistical structure of variability observed to occur in the neuron's discharge.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.155.3764.842