Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation

FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction) 1 . This reaction is well documented 2,3 and the following sequence is generally accepted: (a) Formation of electrophilic species: (b) Reaction with doubl...

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Veröffentlicht in:Nature (London) 1966-06, Vol.210 (5043), p.1386-1388
Hauptverfasser: JONES, DENNIS, GRESHAM, G. AUSTIN
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description FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction) 1 . This reaction is well documented 2,3 and the following sequence is generally accepted: (a) Formation of electrophilic species: (b) Reaction with double bond:
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subjects Fatty Acids
Formaldehyde
Histological Techniques
Humanities and Social Sciences
letter
multidisciplinary
Science
title Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation
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