Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation
FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction) 1 . This reaction is well documented 2,3 and the following sequence is generally accepted: (a) Formation of electrophilic species: (b) Reaction with doubl...
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Veröffentlicht in: | Nature (London) 1966-06, Vol.210 (5043), p.1386-1388 |
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description | FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction)
1
. This reaction is well documented
2,3
and the following sequence is generally accepted: (a) Formation of electrophilic species:
(b) Reaction with double bond: |
doi_str_mv | 10.1038/2101386b0 |
format | Article |
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1
. This reaction is well documented
2,3
and the following sequence is generally accepted: (a) Formation of electrophilic species:
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1
. This reaction is well documented
2,3
and the following sequence is generally accepted: (a) Formation of electrophilic species:
(b) Reaction with double bond:</description><subject>Fatty Acids</subject><subject>Formaldehyde</subject><subject>Histological Techniques</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Science</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEFLwzAYhoMoc04P_gAhJ0Ghmq9pk-w4hnXCQBjuXNI02TK6ZiYpun9vx8ZOnr7D-_DA9yB0D-QFCBWvKRCgglXkAg0h4yzJmOCXaEhIKhIiKLtGNyFsCCE58GyABjmlLKdkiBYLLVW0rsXO4ML5rWxqvd7XGv_YuMbLNsjYeRl1jQsZ4x5PlK0Drjtv2xWe2RBd41ZWyQYX9lceTLfoysgm6LvTHaFl8fY1nSXzz_eP6WSeKAp5TAyraJ4DjKkCSkUGteIqo6lgaUZ4ZUCABsJymXPGq6oCLhQ3hoylElIaTUfo8ejdeffd6RDLrQ1KN41stetCKTJKelfag09HUHkXgtem3Hm7lX5fAikP_cpzv559OEm7aqvrM3kK1u_Pxz3sDgW0Lzeu823_5z-yP4UVd3I</recordid><startdate>19660625</startdate><enddate>19660625</enddate><creator>JONES, DENNIS</creator><creator>GRESHAM, G. AUSTIN</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19660625</creationdate><title>Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation</title><author>JONES, DENNIS ; GRESHAM, G. AUSTIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-f6b3551193c133841dc7c432862407bf181e1065a5767bbb178c7ff09ac8aafe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Fatty Acids</topic><topic>Formaldehyde</topic><topic>Histological Techniques</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Science</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JONES, DENNIS</creatorcontrib><creatorcontrib>GRESHAM, G. AUSTIN</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JONES, DENNIS</au><au>GRESHAM, G. AUSTIN</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1966-06-25</date><risdate>1966</risdate><volume>210</volume><issue>5043</issue><spage>1386</spage><epage>1388</epage><pages>1386-1388</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction)
1
. This reaction is well documented
2,3
and the following sequence is generally accepted: (a) Formation of electrophilic species:
(b) Reaction with double bond:</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>5336530</pmid><doi>10.1038/2101386b0</doi><tpages>3</tpages></addata></record> |
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subjects | Fatty Acids Formaldehyde Histological Techniques Humanities and Social Sciences letter multidisciplinary Science |
title | Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation |
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