Altered Ribosomal Protein in Streptomycin-Dependent Escherichia coli

Altered Ribosomal Protein in Streptomycin-Dependent Escherichia coli

We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altere in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribo...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1969-12, Vol.166 (3910), p.1282-1284
Hauptverfasser: Birge, E. A., Kurland, C. G.
Format: Artikel
Sprache:eng
Schlagworte:
Bacterial Proteins - isolation & purification
Carbon Isotopes
Drug Resistance, Microbial
Escherichia coli
Genetic loci
Phenotypes
Phenylalanine - metabolism
Ribosomal proteins
Ribosomes
RNA
Streptomycin - pharmacology
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Zusammenfassung:We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altere in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribosomes resistant to streptomycin.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.166.3910.1282