Inhibition of parallel flux and augmentation of counter flux shown by transport models not involving a mobile carrier

Two models for mediated transport are described. The “allosteric” model involves transition of a combining site between two alternate shapes. The “H bond” model involves transition of a combining site between two alternate hydrogen bonded states. In both cases, the alternate forms have different dir...

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Veröffentlicht in:Journal of theoretical biology 1966-02, Vol.10 (2), p.301-306
1. Verfasser: Vidaver, George A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Two models for mediated transport are described. The “allosteric” model involves transition of a combining site between two alternate shapes. The “H bond” model involves transition of a combining site between two alternate hydrogen bonded states. In both cases, the alternate forms have different directional properties. These models are kinetically equivalent to a mobile carrier model.
ISSN:0022-5193
1095-8541
DOI:10.1016/0022-5193(66)90128-7