Colorimetric method for determination of serum hyaluronidase activity
A colorimetric method for determination of serum hyaluronidase activity is described. The method is based on the quantitation of N-acetylglucosamine end groups liberated from hyaluronic acid. The results are expressed as the ratio of product formation by serum to product formation by a bovine testic...
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| Veröffentlicht in: | Clinica chimica acta 1966-06, Vol.13 (6), p.746-752 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | A colorimetric method for determination of serum hyaluronidase activity is described. The method is based on the quantitation of
N-acetylglucosamine end groups liberated from hyaluronic acid. The results are expressed as the ratio of product formation by serum to product formation by a bovine testicular hyaluronidase preparation.
The serum hyaluronidase activities of normal individuals and patients with several rheumatic diseases have been compared. Eleven of 35 patients with active rheumatoid arthritis were found to have serum hyaluronidase activity above the normal range. |
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| ISSN: | 0009-8981 1873-3492 |
| DOI: | 10.1016/0009-8981(66)90142-2 |