Polarographic Study of Pteridines

Polarographic Study of Pteridines

The electronegativity of the half-wave potentials of a series of pteridine congeners was found to be related to the substituent groups. The 2,4,7-triaminopteridines, 7-substituted 4-amino-2-aryl-6-pteridinecarboxarnides, and 4,7-diamino-2-aryl-6-pteridinecarboxamides were characterized, in that orde...

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Veröffentlicht in:Journal of pharmaceutical sciences 1966-06, Vol.55 (6), p.555-560
Hauptverfasser: Lapidus, Milton, Rosenthale, Marvin E.
Format: Artikel
Sprache:eng
Schlagworte:
Diuretics - analysis
Oxidation-Reduction
Polarography
Pteridines - analysis
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Beschreibung
Zusammenfassung:The electronegativity of the half-wave potentials of a series of pteridine congeners was found to be related to the substituent groups. The 2,4,7-triaminopteridines, 7-substituted 4-amino-2-aryl-6-pteridinecarboxarnides, and 4,7-diamino-2-aryl-6-pteridinecarboxamides were characterized, in that order, by decreasingly lower electronegative half-wave potentials.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600550604