Curare as a Neuromuscular Blocking Agent in Insects

Topical application of curare produced no effects on electrical activity in single flight-muscle fibers of the fly Sarcophage. However, the intra-abdominal injection of curare induced a neuromuscular block similar to that described for vertebrates. The general refractoriness of some insects to chemi...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1966-11, Vol.154 (3752), p.1023-1024
1. Verfasser:	McCann, Frances V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Abnormal hemoglobins Amino acids Animals Children Curare - administration & dosage Curare - pharmacology Diptera - drug effects Electrophysiology - drug effects Heart Hemoglobins Medical genetics Muscles - drug effects Neuromuscular blocking agents Sarcophagi Topical application
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Zusammenfassung:	Topical application of curare produced no effects on electrical activity in single flight-muscle fibers of the fly Sarcophage. However, the intra-abdominal injection of curare induced a neuromuscular block similar to that described for vertebrates. The general refractoriness of some insects to chemical agents may well be due to the method of application.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.154.3752.1023