The metabolism of tremorine—the identification of 1,4-di (2-oxopyrrolidino)-2-butyne (symmetric dioxotremorine)

The metabolism of tremorine—the identification of 1,4-di (2-oxopyrrolidino)-2-butyne (symmetric dioxotremorine)

A new metabolite of tremorine, Symmetrie dioxotremorine [1,4-di(2-oxopyrrolidino)-2-butyne] has been identified in rats by the use of combined gas chromatography-mass spectrometry.

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Veröffentlicht in:Biochemical pharmacology 1969-07, Vol.18 (7), p.1549-1551
Hauptverfasser: Hammar, Carl-Gustaf, Hammer, Wolfgang, Holmstedt, Bo, Karlén, Bo, Sjöqvist, Folke, Vessman, Jörgen
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Chromatography, Gas
Male
Rats
Spectrum Analysis
Tremorine - analysis
Tremorine - chemical synthesis
Tremorine - metabolism
Urine - analysis
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Zusammenfassung:A new metabolite of tremorine, Symmetrie dioxotremorine [1,4-di(2-oxopyrrolidino)-2-butyne] has been identified in rats by the use of combined gas chromatography-mass spectrometry.
ISSN:0006-2952
1873-2968
DOI:10.1016/0006-2952(69)90141-5