EFFECT OF INSULIN ON THE INCORPORATION OF 14C OF RADIOACTIVE GLUCOSE INTO GLYCOGEN AND CARBON DIOXIDE IN CEREBRAL CORTICAL SLICES

EFFECT OF INSULIN ON THE INCORPORATION OF 14C OF RADIOACTIVE GLUCOSE INTO GLYCOGEN AND CARBON DIOXIDE IN CEREBRAL CORTICAL SLICES

— Slices from the cerebral cortices of normal and alloxan‐diabetic rats were incubated with [U‐24C]glucose. When insulin was added to the incubation medium the incorporation of 14C into glycogen was significantly increased in both groups. Insulin did not appear to have any significant effect on the...

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Veröffentlicht in:Journal of neurochemistry 1969-09, Vol.16 (9), p.1389-1392
Hauptverfasser: Visweswaran, P., Prasannan, K. G., Subrahmanyam, K.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Carbon Dioxide - metabolism
Carbon Isotopes
Cerebral Cortex - drug effects
Cerebral Cortex - metabolism
Diabetes Mellitus, Experimental - metabolism
Glucose - metabolism
Glycogen - metabolism
In Vitro Techniques
Insulin - pharmacology
Rats
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Zusammenfassung:— Slices from the cerebral cortices of normal and alloxan‐diabetic rats were incubated with [U‐24C]glucose. When insulin was added to the incubation medium the incorporation of 14C into glycogen was significantly increased in both groups. Insulin did not appear to have any significant effect on the incorporation of 14C into carbon dioxide.
ISSN:0022-3042
1471-4159
DOI:10.1111/j.1471-4159.1969.tb05990.x