Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line

A hybrid of Ehrlich ascites tumour cells and polyoma-transformed hamster cells can be used to immunize mice against the Ehrlich ascites tumour. The hybrid cell is analogous to an attenuated tumour cell and this method of tumour immunization can be adapted for the detection of tumour antigens.

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Veröffentlicht in:Nature (London) 1969-09, Vol.223 (5210), p.1018-1022
Hauptverfasser: WATKINS, J. F, CHEN, L
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CHEN, L
description A hybrid of Ehrlich ascites tumour cells and polyoma-transformed hamster cells can be used to immunize mice against the Ehrlich ascites tumour. The hybrid cell is analogous to an attenuated tumour cell and this method of tumour immunization can be adapted for the detection of tumour antigens.
doi_str_mv 10.1038/2231018a0
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source MEDLINE; Springer Nature - Complete Springer Journals; Nature Journals Online
subjects Animals
Carcinoma, Ehrlich Tumor - immunology
Cell Line
Cell Transformation, Neoplastic
Clone Cells
Cricetinae
Culture Techniques
Humanities and Social Sciences
Hybridization, Genetic
Immune Sera
Karyotyping
Methods
Mice
Microscopy, Phase-Contrast
multidisciplinary
Polyomavirus
Science
Science (multidisciplinary)
title Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line
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