Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line

Immunization of Mice against Ehrlich Ascites Tumour using a Hamster/Ehrlich Ascites Tumour Hybrid Cell Line

A hybrid of Ehrlich ascites tumour cells and polyoma-transformed hamster cells can be used to immunize mice against the Ehrlich ascites tumour. The hybrid cell is analogous to an attenuated tumour cell and this method of tumour immunization can be adapted for the detection of tumour antigens.

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Bibliographische Detailangaben
Veröffentlicht in:Nature (London) 1969-09, Vol.223 (5210), p.1018-1022
Hauptverfasser: WATKINS, J. F, CHEN, L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Carcinoma, Ehrlich Tumor - immunology
Cell Line
Cell Transformation, Neoplastic
Clone Cells
Cricetinae
Culture Techniques
Humanities and Social Sciences
Hybridization, Genetic
Immune Sera
Karyotyping
Methods
Mice
Microscopy, Phase-Contrast
multidisciplinary
Polyomavirus
Science
Science (multidisciplinary)
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Beschreibung
Zusammenfassung:A hybrid of Ehrlich ascites tumour cells and polyoma-transformed hamster cells can be used to immunize mice against the Ehrlich ascites tumour. The hybrid cell is analogous to an attenuated tumour cell and this method of tumour immunization can be adapted for the detection of tumour antigens.
ISSN:0028-0836
1476-4687
DOI:10.1038/2231018a0