RETICULOENDOTHELIAL BLOCKADE PRODUCED BY ANTILYMPHOCYTE SERUM

Injection of antiserum to mouse lymphocytes (A.L.S.) was found to impair clearance from the bloodstream of colloidal carbon and microaggregated human serum-albumin in mice. Intravenous injection of A.L.S. produced immediate, profound, and prolonged blockade of the reticuloendothelial system and was...

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Veröffentlicht in:The Lancet (British edition) 1969-01, Vol.294 (7615), p.297-298
Hauptverfasser: Sheagren, JohnN, Edelin, JosephB, Barth, RolfF, Malmgren, RichardA
Format: Artikel
Sprache:eng
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Zusammenfassung:Injection of antiserum to mouse lymphocytes (A.L.S.) was found to impair clearance from the bloodstream of colloidal carbon and microaggregated human serum-albumin in mice. Intravenous injection of A.L.S. produced immediate, profound, and prolonged blockade of the reticuloendothelial system and was more effective than the same dose administered intraperitoneally.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(69)90057-9