IgA with "Secretory Piece" in Bovine Colostrum and Saliva
WE have shown that in bovine colostrum and saliva there is a secretory IgA with a sedimentation, coefficient of 11 S and a secretory piece, previously unknown and comparable with the 11 S IgA described in human and rabbit external secretions. These secretory IgA contain molecules of 7 S IgA with an...
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Veröffentlicht in: | Nature (London) 1969-08, Vol.223 (5209), p.952-955 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | WE have shown that in bovine colostrum and saliva there is a secretory IgA with a sedimentation, coefficient of 11
S
and a secretory piece, previously unknown and comparable with the 11
S
IgA described in human and rabbit external secretions. These secretory IgA contain molecules of 7
S
IgA with an additional protein segment called the transport or secretory piece
1–5
. Furthermore, the free form of the secretory piece is identified in bovine colostrum and also in mature milk which contains very little IgA. |
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ISSN: | 0028-0836 1476-4687 |
DOI: | 10.1038/223952a0 |