IgA with "Secretory Piece" in Bovine Colostrum and Saliva

WE have shown that in bovine colostrum and saliva there is a secretory IgA with a sedimentation, coefficient of 11 S and a secretory piece, previously unknown and comparable with the 11 S IgA described in human and rabbit external secretions. These secretory IgA contain molecules of 7 S IgA with an...

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Veröffentlicht in:Nature (London) 1969-08, Vol.223 (5209), p.952-955
Hauptverfasser: MACH, J.-P, PAHUD, J.-J, ISLIKER, H
Format: Artikel
Sprache:eng
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Zusammenfassung:WE have shown that in bovine colostrum and saliva there is a secretory IgA with a sedimentation, coefficient of 11 S and a secretory piece, previously unknown and comparable with the 11 S IgA described in human and rabbit external secretions. These secretory IgA contain molecules of 7 S IgA with an additional protein segment called the transport or secretory piece 1–5 . Furthermore, the free form of the secretory piece is identified in bovine colostrum and also in mature milk which contains very little IgA.
ISSN:0028-0836
1476-4687
DOI:10.1038/223952a0