Viral Infection Across Species Barriers: Reversible Alteration of Murine Sarcoma Virus for Growth in Cat Cells

Infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus gave rise to a defective, focus-forming virus which propagated in cat cells, but not in mouse cells. This virus, apparently enveloped with a feline leukemia virus coat, was later subj...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1969-08, Vol.165 (3894), p.714-716
Hauptverfasser:	Fischinger, Peter J., O'Connor, Timothy E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cats Cell growth Culture Techniques Embryonic cells Embryos Fibroblasts Infections Leukemia Mice Moloney murine leukemia virus Murine leukemia virus Murine sarcoma viruses Neurons Retroviridae Species Specificity Virus Cultivation Viruses
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Beschreibung
Zusammenfassung:	Infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus gave rise to a defective, focus-forming virus which propagated in cat cells, but not in mouse cells. This virus, apparently enveloped with a feline leukemia virus coat, was later subjected to aggregation with murine leukemia virus, whereupon it regained the capacity for growth in mouse cells.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.165.3894.714