Effects of positive pressure ventilation of the mother upon the acid-base state of the fetus

The effect of maternal hyperventilation in absence of hypocapnia upon the fetus was investigated in pregnant guinea pigs. It was shown that in addition to the maternal systemic hypotension which can be induced by hypocapnia, the mechanical effects of positive pressure ventilation can contribute to t...

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Veröffentlicht in:	American journal of obstetrics and gynecology 1965-09, Vol.93 (2), p.269-273
Hauptverfasser:	Morishima, Hisayo O., Daniel, Salha S., Adamsons, Karlis, James, L.Stanley
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-Base Equilibrium Acidosis Animals Female Fetal Diseases Fetus Guinea Pigs Hyperventilation Mothers Old Medline Positive-Pressure Respiration Pregnancy Pregnancy, Animal
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Zusammenfassung:	The effect of maternal hyperventilation in absence of hypocapnia upon the fetus was investigated in pregnant guinea pigs. It was shown that in addition to the maternal systemic hypotension which can be induced by hypocapnia, the mechanical effects of positive pressure ventilation can contribute to the production of metabolic acidosis in the fetus probably by diminishing the venous return in the mother and thus causing the decreased placental perfusion.
ISSN:	0002-9378 1097-6868
DOI:	10.1016/0002-9378(65)90668-X