2-(2-Aminoethylamino)-1,2-diphenylethanol derivatives, a new class of topical antiinflammatory agents

A number of analogues and derivatives of the title compound were synthesized and evaluated in a new test procedure used to detect topical antiinflammatory activity. Some general comments regarding observation on the structure-activity relationship of these compounds are made.

Bibliographische Detailangaben

Veröffentlicht in:	Journal of medicinal chemistry 1977-10, Vol.20 (10), p.1268-1272
Hauptverfasser:	Fryer, R. Ian, Boris, Alfred, Earley, James V, Reeder, Earl
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Anti-Inflammatory Agents - chemical synthesis Ethanol - analogs & derivatives Granuloma - physiopathology Inflammation - physiopathology Phenylethyl Alcohol - analogs & derivatives Phenylethyl Alcohol - chemical synthesis Phenylethyl Alcohol - pharmacology Rats Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!