Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies
Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by c...
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Veröffentlicht in: | American journal of clinical pathology 1977-09, Vol.68 (3), p.343-346 |
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creator | Niebojewski, R A Aguilar-Torres, F G Rytel, M W |
description | Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169). |
doi_str_mv | 10.1093/ajcp/68.3.343 |
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The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. 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The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169).</description><subject>Antibodies, Viral - analysis</subject><subject>Complement Fixation Tests</subject><subject>Counterimmunoelectrophoresis - methods</subject><subject>Cross Reactions</subject><subject>Cytomegalovirus - immunology</subject><subject>Cytomegalovirus Infections - diagnosis</subject><subject>Cytomegalovirus Infections - immunology</subject><subject>Humans</subject><subject>Immunoelectrophoresis - methods</subject><subject>Kidney Transplantation</subject><subject>Postoperative Complications - diagnosis</subject><subject>Transplantation, Homologous</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtPwzAURi3EqxRGNoZMbGn9ih9jhXhJlVhgQ7Kc-AZcJXGwE6T-e1JaxF3ucM_3SfcgdE3wgmDNlnZT9UuhFmzBODtCM6I5y6Wk9BjNMMY010Syc3SR0gZjQhXmZ-iUaKm4mKH3Vd83vrKDD10W6qwKYzdA9G07dgEaqIYY-s8QIfmU-S6LtvcuczBMl7_IdggtfNgmfPs4psx2gy-D85Au0UltmwRXhz1Hbw_3r3dP-frl8flutc4rquSQFyA5J7KgVsA0RNUYdFELWZaaFEzX2rna1UoJLpyQmklHpSsqagvNwBE2R7f73j6GrxHSYFqfKmga20EYk1EcC4almMB8D1YxpBShNv30qo1bQ7DZyTQ7mUYow8wkc-JvDsVj2YL7p3_tsR81H3Mk</recordid><startdate>197709</startdate><enddate>197709</enddate><creator>Niebojewski, R A</creator><creator>Aguilar-Torres, F G</creator><creator>Rytel, M W</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197709</creationdate><title>Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies</title><author>Niebojewski, R A ; Aguilar-Torres, F G ; Rytel, M W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c287t-5e7441752a6eeee18f0e95f67bb91539f9ddfdf88646d67937d27d5c2a593ed13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Antibodies, Viral - analysis</topic><topic>Complement Fixation Tests</topic><topic>Counterimmunoelectrophoresis - methods</topic><topic>Cross Reactions</topic><topic>Cytomegalovirus - immunology</topic><topic>Cytomegalovirus Infections - diagnosis</topic><topic>Cytomegalovirus Infections - immunology</topic><topic>Humans</topic><topic>Immunoelectrophoresis - methods</topic><topic>Kidney Transplantation</topic><topic>Postoperative Complications - diagnosis</topic><topic>Transplantation, Homologous</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Niebojewski, R A</creatorcontrib><creatorcontrib>Aguilar-Torres, F G</creatorcontrib><creatorcontrib>Rytel, M W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Niebojewski, R A</au><au>Aguilar-Torres, F G</au><au>Rytel, M W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>1977-09</date><risdate>1977</risdate><volume>68</volume><issue>3</issue><spage>343</spage><epage>346</epage><pages>343-346</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><abstract>Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169).</abstract><cop>England</cop><pmid>197846</pmid><doi>10.1093/ajcp/68.3.343</doi><tpages>4</tpages></addata></record> |
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subjects | Antibodies, Viral - analysis Complement Fixation Tests Counterimmunoelectrophoresis - methods Cross Reactions Cytomegalovirus - immunology Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - immunology Humans Immunoelectrophoresis - methods Kidney Transplantation Postoperative Complications - diagnosis Transplantation, Homologous |
title | Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies |
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