Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies

Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by c...

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Veröffentlicht in:	American journal of clinical pathology 1977-09, Vol.68 (3), p.343-346
Hauptverfasser:	Niebojewski, R A, Aguilar-Torres, F G, Rytel, M W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral - analysis Complement Fixation Tests Counterimmunoelectrophoresis - methods Cross Reactions Cytomegalovirus - immunology Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - immunology Humans Immunoelectrophoresis - methods Kidney Transplantation Postoperative Complications - diagnosis Transplantation, Homologous
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Zusammenfassung:	Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169).
ISSN:	0002-9173 1943-7722
DOI:	10.1093/ajcp/68.3.343