SULFOMYCINS, A SERIES OF NEW SULFUR-CONTAINING ANTIBIOTICS. I: ISOLATION, PURIFICATION AND PROPERTIES

Isolation of a series of antibiotics produced by a new variety of Streptomyces viridochromogenes was attempted, and three main components were obtained as amorphous powders. They were primarily active against Grampositive bacteria, anaerobic bacteria and mycoplasma and characterized as new members o...

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Veröffentlicht in:	Journal of antibiotics 1969/01/25, Vol.22(1), pp.12-17
Hauptverfasser:	EGAWA, YOSHIYUKI, UMINO, KIMIO, TAMURA, YOSHIKAZU, SHIMIZU, MASAAKI, KANEKO, KENYO, SAKURAZAWA, MASAHARU, AWATAGUCHI, SHIGEMI, OKUDA, TOMOHARU
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - analysis Animals Anti-Bacterial Agents - analysis Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Bacteria - drug effects Chemical Phenomena Chemistry, Physical Chromatography Chromatography, Thin Layer Fungi - drug effects Infrared Rays Magnetic Resonance Spectroscopy Mice Mycoplasma - drug effects Optical Rotatory Dispersion Peptides - analysis Silicon Dioxide Spectrum Analysis Staphylococcal Infections - drug therapy Streptomyces Sulfur - analysis Ultraviolet Rays
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Zusammenfassung:	Isolation of a series of antibiotics produced by a new variety of Streptomyces viridochromogenes was attempted, and three main components were obtained as amorphous powders. They were primarily active against Grampositive bacteria, anaerobic bacteria and mycoplasma and characterized as new members of sulfur-containing peptidic antibiotics. The antibiotic complex was named sulfomycin.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.22.12