Serum glycoproteins in coronary artery disease

Serum glycoproteins in coronary artery disease

Serum glycoprotein levels were compared in two groups of age- and sex-matched patients, 15 with coronary artery disease and 14 normal controls. While total glycoprotein levels were increased in the coronary group, significantly higher levels were found in only five of 16 glycoproteins--C3c haptoglob...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 1977-09, Vol.56 (3), p.359-362
Hauptverfasser: Snyder, S, Coodley, E L, Durham, B C, Pennock, R S
Format: Artikel
Sprache:eng
Schlagworte:
Arteriosclerosis - etiology
Complement C3 - analysis
Coronary Disease - blood
Female
Glycoproteins - blood
Haptoglobins - analysis
Humans
Hyperlipidemias - etiology
Male
Middle Aged
Transferrin - analysis
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Zusammenfassung:Serum glycoprotein levels were compared in two groups of age- and sex-matched patients, 15 with coronary artery disease and 14 normal controls. While total glycoprotein levels were increased in the coronary group, significantly higher levels were found in only five of 16 glycoproteins--C3c haptoglobin, GC-globulin, alpha1-acid glycoprotein, and C3 activator--with no change in 10 other glycoproteins and significant decrease in transferrin. This study demonstrates what appears to be a glycoprotein profile in coronary artery disease and reviews possible interactions of glycoproteins with known risk factors in atherogenesis.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.56.3.359